Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response

Interleukin-1 (IL-1), the ‘gatekeeper’ of inflammation, is the apical cytokine in a signalling cascade that drives the early response to injury or infection. Expression, processing and secretion of IL-1 are tightly controlled, and dysregulated IL-1 signalling has been implicated in a number of patho...

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Detalles Bibliográficos
Autores principales: Ogryzko, Nikolay V., Hoggett, Emily E., Solaymani-Kohal, Sara, Tazzyman, Simon, Chico, Timothy J. A., Renshaw, Stephen A., Wilson, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917246/
https://www.ncbi.nlm.nih.gov/pubmed/24203886
http://dx.doi.org/10.1242/dmm.013029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917246/
https://www.ncbi.nlm.nih.gov/pubmed/24203886
http://dx.doi.org/10.1242/dmm.013029

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