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6-Bromoisatin Found in Muricid Mollusc Extracts Inhibits Colon Cancer Cell Proliferation and Induces Apoptosis, Preventing Early Stage Tumor Formation in a Colorectal Cancer Rodent Model

Muricid molluscs are a natural source of brominated isatin with anticancer activity. The aim of this study was to examine the safety and efficacy of synthetic 6-bromoisatin for reducing the risk of early stage colorectal tumor formation. The purity of 6-bromoisatin was confirmed by (1)H NMR spectros...

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Detalles Bibliográficos
Autores principales: Esmaeelian, Babak, Abbott, Catherine A., Le Leu, Richard K., Benkendorff, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917258/
https://www.ncbi.nlm.nih.gov/pubmed/24368567
http://dx.doi.org/10.3390/md12010017