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Marine Natural Products with P-Glycoprotein Inhibitor Properties

P-glycoprotein (P-gp) is a protein belonging to the ATP-binding cassette (ABC) transporters superfamily that has clinical relevance due to its role in drug metabolism and multi-drug resistance (MDR) in several human pathogens and diseases. P-gp is a major cause of drug resistance in cancer, parasiti...

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Detalles Bibliográficos
Autores principales: Lopez, Dioxelis, Martinez-Luis, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917285/
https://www.ncbi.nlm.nih.gov/pubmed/24451193
http://dx.doi.org/10.3390/md12010525