Cargando…

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development: Part 3—Introduction to Pharmacodynamic Modeling Methods

Population pharmacodynamic (PD) models describe the time course of drug effects, relating exposure to response, and providing a more robust understanding of drug action than single assessments. PD models can test alternative dose regimens through simulation, allowing for informed assessment of poten...

Descripción completa

Detalles Bibliográficos
Autores principales: Upton, R N, Mould, D R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917320/
https://www.ncbi.nlm.nih.gov/pubmed/24384783
http://dx.doi.org/10.1038/psp.2013.71