Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease

BACKGROUND: Lafora disease is an autosomal recessive form of progressive myoclonic epilepsy caused by defects in the EPM2A and EPM2B genes. Primary symptoms of the pathology include seizures, ataxia, myoclonus, and progressive development of severe dementia. Lafora disease can be caused by defects i...

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Detalles Bibliográficos
Autores principales: Ortolano, Saida, Vieitez, Irene, Agis-Balboa, Roberto Carlos, Spuch, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917365/
https://www.ncbi.nlm.nih.gov/pubmed/24472629
http://dx.doi.org/10.1186/1756-6606-7-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917365/
https://www.ncbi.nlm.nih.gov/pubmed/24472629
http://dx.doi.org/10.1186/1756-6606-7-7

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