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Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease
BACKGROUND: Lafora disease is an autosomal recessive form of progressive myoclonic epilepsy caused by defects in the EPM2A and EPM2B genes. Primary symptoms of the pathology include seizures, ataxia, myoclonus, and progressive development of severe dementia. Lafora disease can be caused by defects i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917365/ https://www.ncbi.nlm.nih.gov/pubmed/24472629 http://dx.doi.org/10.1186/1756-6606-7-7 |