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Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine
BACKGROUND: GATA transcription factors are essential for self-renewal of the small intestinal epithelium. Gata4 is expressed in the proximal 85% of small intestine while Gata6 is expressed throughout the length of small intestine. Deletion of intestinal Gata4 and Gata6 results in an altered prolifer...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917371/ https://www.ncbi.nlm.nih.gov/pubmed/24472151 http://dx.doi.org/10.1186/1471-2199-15-3 |