Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine

BACKGROUND: GATA transcription factors are essential for self-renewal of the small intestinal epithelium. Gata4 is expressed in the proximal 85% of small intestine while Gata6 is expressed throughout the length of small intestine. Deletion of intestinal Gata4 and Gata6 results in an altered prolifer...

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Detalles Bibliográficos
Autores principales: Aronson, Boaz E, Stapleton, Kelly A, Vissers, Laurens ATM, Stokhuijzen, Eva, Bruijnzeel, Hanneke, Krasinski, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917371/
https://www.ncbi.nlm.nih.gov/pubmed/24472151
http://dx.doi.org/10.1186/1471-2199-15-3

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