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Effect of bevacizumab (Avastin™) on mitochondrial function of in vitro retinal pigment epithelial, neurosensory retinal and microvascular endothelial cells

PURPOSE: To evaluate the effect of bevacizumab on the mitochondrial function of human retinal pigment epithelial (ARPE-19), rat neurosensory retinal (R28) and human microvascular endothelial (HMVEC) cells in culture. MATERIALS AND METHODS: ARPE-19 and R28 cells were treated with 0.125, 0.25, 0.50 an...

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Detalles Bibliográficos
Autores principales: Luthra, Saurabh, Sharma, Ashish, Dong, Joyce, Neekhra, Aneesh, Gramajo, Ana L, Seigel, Gail M, Kenney, M Cristina, Kuppermann, Baruch D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917387/
https://www.ncbi.nlm.nih.gov/pubmed/24413824
http://dx.doi.org/10.4103/0301-4738.124750