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CCR5 as a Natural and Modulated Target for Inhibition of HIV

Human immunodeficiency virus type 1 (HIV-1) infection of target cells requires CD4 and a co-receptor, predominantly the chemokine receptor CCR5. CCR5-delta32 homozygosity results in a truncated protein providing natural protection against HIV infection—this without detrimental effects to the host—an...

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Detalles Bibliográficos
Autores principales: Burke, Bryan P., Boyd, Maureen P., Impey, Helen, Breton, Louis R., Bartlett, Jeffrey S., Symonds, Geoff P., Hütter, Gero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917431/
https://www.ncbi.nlm.nih.gov/pubmed/24381033
http://dx.doi.org/10.3390/v6010054