Cargando…
CCR5 as a Natural and Modulated Target for Inhibition of HIV
Human immunodeficiency virus type 1 (HIV-1) infection of target cells requires CD4 and a co-receptor, predominantly the chemokine receptor CCR5. CCR5-delta32 homozygosity results in a truncated protein providing natural protection against HIV infection—this without detrimental effects to the host—an...
Autores principales: | Burke, Bryan P., Boyd, Maureen P., Impey, Helen, Breton, Louis R., Bartlett, Jeffrey S., Symonds, Geoff P., Hütter, Gero |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917431/ https://www.ncbi.nlm.nih.gov/pubmed/24381033 http://dx.doi.org/10.3390/v6010054 |
Ejemplares similares
-
CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape
por: Hütter, Gero, et al.
Publicado: (2015) -
Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor
por: Wolstein, Orit, et al.
Publicado: (2014) -
Clearing the HIV reservoir by transplanting CCR5 deficient stem cells
por: Hütter, Gero
Publicado: (2011) -
Eradication of HIV by Transplantation of CCR5-Deficient Hematopoietic Stem Cells
por: Hütter, Gero, et al.
Publicado: (2011) -
Coregulation of HIV-1 dependency factors in individuals heterozygous to the CCR5-delta32 deletion
por: Hütter, Gero, et al.
Publicado: (2013)