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Analysis of Essential Viral Gene Functions after Highly Efficient Adenofection of Cells with Cloned Human Cytomegalovirus Genomes

Human cytomegalovirus (HCMV) has a large 240 kb genome that may encode more than 700 gene products with many of them remaining uncharacterized. Mutagenesis of bacterial artificial chromosome (BAC)-cloned CMV genomes has greatly facilitated the analysis of viral gene functions. However, the roles of...

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Detalles Bibliográficos
Autores principales: Elbasani, Endrit, Gabaev, Ildar, Steinbrück, Lars, Messerle, Martin, Borst, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917448/
https://www.ncbi.nlm.nih.gov/pubmed/24452007
http://dx.doi.org/10.3390/v6010354