Saporin Conjugated Monoclonal Antibody to the Transcobalamin Receptor TCblR/CD320 Is Effective in Targeting and Destroying Cancer Cells

Cobalamin uptake into cells is mediated by the CD320 receptor for transcobalamin-bound cobalamin. Optimum receptor expression is associated with proliferating cells and therefore, in many cancers this receptor expression is up regulated. Delivering drugs or toxins via this receptor provides increase...

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Detalles Bibliográficos
Autores principales: Quadros, Edward V., Nakayama, Yasumi, Sequeira, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917558/
https://www.ncbi.nlm.nih.gov/pubmed/24511425
http://dx.doi.org/10.4236/jct.2013.46122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917558/
https://www.ncbi.nlm.nih.gov/pubmed/24511425
http://dx.doi.org/10.4236/jct.2013.46122

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