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Cytocidal Activities of Topoisomerase 1 Inhibitors and 5-Azacytidine against Pheochromocytoma/Paraganglioma Cells in Primary Human Tumor Cultures and Mouse Cell Lines

There is currently no effective treatment for metastatic pheochromocytomas and paragangliomas. A deficiency in current chemotherapy regimens is that the metastases usually grow very slowly. Drugs that target dividing tumor cells have therefore had limited success. To improve treatment, new strategie...

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Detalles Bibliográficos
Autores principales: Powers, James F., Korgaonkar, Parimal G., Fliedner, Stephanie, Giubellino, Alessio, Sahagian, Karel Pacak, G. Gary., Tischler, Arthur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917832/
https://www.ncbi.nlm.nih.gov/pubmed/24516563
http://dx.doi.org/10.1371/journal.pone.0087807