Ectopic Cerebellar Cell Migration Causes Maldevelopment of Purkinje Cells and Abnormal Motor Behaviour in Cxcr4 Null Mice

SDF-1/CXCR4 signalling plays an important role in neuronal cell migration and brain development. However, the impact of CXCR4 deficiency in the postnatal mouse brain is still poorly understood. Here, we demonstrate the importance of CXCR4 on cerebellar development and motor behaviour by conditional...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Guo-Jen, Edwards, Andrew, Tsai, Cheng-Yu, Lee, Yi-Shin, Peng, Lei, Era, Takumi, Hirabayashi, Yoshio, Tsai, Ching-Yen, Nishikawa, Shin-Ichi, Iwakura, Yoichiro, Chen, Shu-Jen, Flint, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917845/
https://www.ncbi.nlm.nih.gov/pubmed/24516532
http://dx.doi.org/10.1371/journal.pone.0086471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917845/
https://www.ncbi.nlm.nih.gov/pubmed/24516532
http://dx.doi.org/10.1371/journal.pone.0086471

Ejemplares similares