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Robust Regression Analysis of Copy Number Variation Data based on a Univariate Score

MOTIVATION: The discovery that copy number variants (CNVs) are widespread in the human genome has motivated development of numerous algorithms that attempt to detect CNVs from intensity data. However, all approaches are plagued by high false discovery rates. Further, because CNVs are characterized b...

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Detalles Bibliográficos
Autores principales: Satten, Glen A., Allen, Andrew S., Ikeda, Morna, Mulle, Jennifer G., Warren, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917847/
https://www.ncbi.nlm.nih.gov/pubmed/24516529
http://dx.doi.org/10.1371/journal.pone.0086272