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New Findings in Cleavage Sites Variability across Groups, Subtypes and Recombinants of Human Immunodeficiency Virus Type 1

BACKGROUND: Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS: In thi...

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Detalles Bibliográficos
Autores principales: Torrecilla, Esther, Llácer Delicado, Teresa, Holguín, África
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917854/
https://www.ncbi.nlm.nih.gov/pubmed/24516589
http://dx.doi.org/10.1371/journal.pone.0088099