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Characterization of 65 Epitope-Specific Dystrophin Monoclonal Antibodies in Canine and Murine Models of Duchenne Muscular Dystrophy by Immunostaining and Western Blot

Epitope-specific monoclonal antibodies can provide unique insights for studying cellular proteins. Dystrophin is one of the largest cytoskeleton proteins encoded by 79 exons. The absence of dystrophin results in Duchenne muscular dystrophy (DMD). Over the last two decades, dozens of exon-specific hu...

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Detalles Bibliográficos
Autores principales: Kodippili, Kasun, Vince, Lauren, Shin, Jin-Hong, Yue, Yongping, Morris, Glenn E., McIntosh, Mark A., Duan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917863/
https://www.ncbi.nlm.nih.gov/pubmed/24516626
http://dx.doi.org/10.1371/journal.pone.0088280