CD8(+) T Cells Mediate Robust Stage-Specific Immunity to P. berghei under Chemoprophylaxis and This Protective Environment Is Not Downregulated by the Presence of Blood-Stage Infection

Sterile protection against malaria infection can be achieved by the inoculation of intact sporozoites while treating concomitantly with the 4-aminoquinoline chloroquine. We present an analysis of protective immunity elicited by successive immunization with Plasmodium berghei sporozoites under chemop...

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Detalles Bibliográficos
Autores principales: Lewis, Matthew D., Pfeil, Johannes, Heiss, Kirsten, Mueller, Ann-Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917870/
https://www.ncbi.nlm.nih.gov/pubmed/24516592
http://dx.doi.org/10.1371/journal.pone.0088117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917870/
https://www.ncbi.nlm.nih.gov/pubmed/24516592
http://dx.doi.org/10.1371/journal.pone.0088117

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