No Major Role for Insulin-Degrading Enzyme in Antigen Presentation by MHC Molecules

Antigen presentation by MHC class I molecules requires degradation of epitope source proteins in the cytosol. Although the preeminent role of the proteasome is clearly established, evidence suggesting a significant role for proteasome-independent generation of class I ligands has been reported repea...

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Detalles Bibliográficos
Autores principales: Culina, Slobodan, Mauvais, François-Xavier, Hsu, Hsiang-Ting, Burgevin, Anne, Guénette, Suzanne, Moser, Anna, van Endert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917890/
https://www.ncbi.nlm.nih.gov/pubmed/24516642
http://dx.doi.org/10.1371/journal.pone.0088365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917890/
https://www.ncbi.nlm.nih.gov/pubmed/24516642
http://dx.doi.org/10.1371/journal.pone.0088365

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