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Using the PfEMP1 Head Structure Binding Motif to Deal a Blow at Severe Malaria

Plasmodium falciparum (Pf) malaria causes 200 million cases worldwide, 8 million being severe and complicated leading to ∼1 million deaths and ∼100,000 abortions annually. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) has been implicated in cytoadherence and infected erythrocyte rose...

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Detalles Bibliográficos
Autores principales: Patarroyo, Manuel E., Alba, Martha Patricia, Curtidor, Hernando, Vanegas, Magnolia, Almonacid, Hannia, Patarroyo, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917906/
https://www.ncbi.nlm.nih.gov/pubmed/24516657
http://dx.doi.org/10.1371/journal.pone.0088420