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Comparison of normalization methods for differential gene expression analysis in RNA-Seq experiments: A matter of relative size of studied transcriptomes

In recent years, RNA-Seq technologies became a powerful tool for transcriptome studies. However, computational methods dedicated to the analysis of high-throughput sequencing data are yet to be standardized. In particular, it is known that the choice of a normalization procedure leads to a great var...

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Detalles Bibliográficos
Autores principales: Maza, Elie, Frasse, Pierre, Senin, Pavel, Bouzayen, Mondher, Zouine, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918003/
https://www.ncbi.nlm.nih.gov/pubmed/26442135
http://dx.doi.org/10.4161/cib.25849