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Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis
Type 2 diabetes mellitus (DM) appears to be a significant risk factor for Alzheimer disease (AD). Insulin and insulin-like growth factor-1 (IGF-1) also have intense effects in the central nervous system (CNS), regulating key processes such as neuronal survival and longevity, as well as learning and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918038/ https://www.ncbi.nlm.nih.gov/pubmed/21435176 http://dx.doi.org/10.1111/j.1582-4934.2011.01318.x |