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Dimeric MHC-peptides inserted into an immunoglobulin scaffold as new immunotherapeutic agents
The interactions of the T cell receptor (TCR) with cognate MHC-peptide and co-stimulatory molecules expressed at surface of antigen presenting cells (APC) leads to activation or tolerance of T cells. The development of molecular biological tools allowed for the preparation of soluble MHC-peptide mol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918039/ https://www.ncbi.nlm.nih.gov/pubmed/21435177 http://dx.doi.org/10.1111/j.1582-4934.2011.01319.x |