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Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis

Histone deacetylases (HDACs) are important regulators of gene expression. Specific structural features and distinct regulative mechanisms rationalize the separation of the 18 different human HDACs into four classes. The class II comprises a heterogeneous group of nuclear and cytosolic HDACs involved...

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Detalles Bibliográficos
Autores principales: Clocchiatti, Andrea, Florean, Cristina, Brancolini, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918040/
https://www.ncbi.nlm.nih.gov/pubmed/21435179
http://dx.doi.org/10.1111/j.1582-4934.2011.01321.x