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Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis
Histone deacetylases (HDACs) are important regulators of gene expression. Specific structural features and distinct regulative mechanisms rationalize the separation of the 18 different human HDACs into four classes. The class II comprises a heterogeneous group of nuclear and cytosolic HDACs involved...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918040/ https://www.ncbi.nlm.nih.gov/pubmed/21435179 http://dx.doi.org/10.1111/j.1582-4934.2011.01321.x |