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Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosis

Lung carcinogenesis is a complex process requiring the acquisition of genetic mutations that confer the malignant phenotype as well as epigenetic alterations that may be both manipulated in the course of therapy. Aberrant gene function and transcriptional silencing by CpG island hypermethylation has...

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Detalles Bibliográficos
Autores principales: Piperi, Christina, Vlastos, Fotis, Farmaki, Elena, Martinet, Nadine, Papavassiliou, Athanasios G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918065/
https://www.ncbi.nlm.nih.gov/pubmed/18363846
http://dx.doi.org/10.1111/j.1582-4934.2008.00309.x