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Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosis
Lung carcinogenesis is a complex process requiring the acquisition of genetic mutations that confer the malignant phenotype as well as epigenetic alterations that may be both manipulated in the course of therapy. Aberrant gene function and transcriptional silencing by CpG island hypermethylation has...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918065/ https://www.ncbi.nlm.nih.gov/pubmed/18363846 http://dx.doi.org/10.1111/j.1582-4934.2008.00309.x |