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Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis

The epidermal growth factor receptor (EGFR) and other members of the EGFR/ErbB receptor family of receptor tyrosine kinases (RTKs) are important regulators of proliferation, angiogenesis, migration, tumorigenesis and metastasis. Overexpression, mutations, deletions and production of autocrine ligand...

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Detalles Bibliográficos
Autores principales: Grandal, Michael Vibo, Madshus, Inger Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918068/
https://www.ncbi.nlm.nih.gov/pubmed/18318691
http://dx.doi.org/10.1111/j.1582-4934.2008.00298.x