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Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis
The epidermal growth factor receptor (EGFR) and other members of the EGFR/ErbB receptor family of receptor tyrosine kinases (RTKs) are important regulators of proliferation, angiogenesis, migration, tumorigenesis and metastasis. Overexpression, mutations, deletions and production of autocrine ligand...
Autores principales: | Grandal, Michael Vibo, Madshus, Inger Helene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918068/ https://www.ncbi.nlm.nih.gov/pubmed/18318691 http://dx.doi.org/10.1111/j.1582-4934.2008.00298.x |
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