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Regulatory roles for histone deacetylation in IL-1β-induced nitric oxide release in pancreatic β-cells

Histone (de)acetylases control gene transcription via modification of the chromatin structure. Herein, we investigated potential roles for histone deacetylation (or hypoacetylation) in interleukin-1β (IL-1β)-mediated inducible nitric oxide synthase (iNOS) and nitric oxide (NO) release in insulin-sec...

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Detalles Bibliográficos
Autores principales: Susick, L, Veluthakal, R, Suresh, M V, Hadden, T, Kowluru, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918073/
https://www.ncbi.nlm.nih.gov/pubmed/18053091
http://dx.doi.org/10.1111/j.1582-4934.2007.00171.x