Cargando…

NFκB mediates IL-1β-induced down-regulation of TβRII through the modulation of Sp3 expression

We previously showed that interleukin-1β (IL-1β) down-regulation of type II TGFβ receptor (TβRII) involves NFκB pathway and requires de novo synthesis of a yet unknown protein. Here, we demonstrate that this effect is mediated through Sp1 site located at position -25 of human TβRII promoter. Inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baugé, C, Beauchef, G, Leclercq, S, Kim, S J, Pujol, J P, Galéra, P, Boumédiene, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918091/ https://www.ncbi.nlm.nih.gov/pubmed/18053089 http://dx.doi.org/10.1111/j.1582-4934.2007.00173.x

Ejemplares similares

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta
por: Baugé, Catherine, et al.
Publicado: (2011)

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-β pathway – implication of C-Krox and Sp1
por: Renard, Emmanuelle, et al.
Publicado: (2008)

PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice
por: Zhang, Jingliang, et al.
Publicado: (2021)

Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention
por: Martín-López, Juana, et al.
Publicado: (2017)

Clinical Implications of TβRII Expression in Breast Cancer
por: Gao, Ningning, et al.
Publicado: (2015)

Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
por: Zhang, Ping, et al.
Publicado: (2015)

Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer
por: Diaz-Chavez, Jose, et al.
Publicado: (2008)

Protein Kinase A in Human Retina: Differential Localization of Cβ, Cα, RIIα, and RIIβ in Photoreceptors Highlights Non-redundancy of Protein Kinase A Subunits
por: Roa, Jinae N., et al.
Publicado: (2021)

Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells
por: Kim, Dong Hyun, et al.
Publicado: (2021)

Gene Silencing of TGFβRII Can Inhibit Glioblastoma Cell Growth
por: Aval, Farzane Ordoni, et al.
Publicado: (2018)

TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism
por: Varadaraj, Archana, et al.
Publicado: (2017)

Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII
por: Mukundan, Ananya, et al.
Publicado: (2022)

Protein kinase C βII and TGFβRII in ω-3 fatty acid–mediated inhibition of colon carcinogenesis
por: Murray, Nicole R., et al.
Publicado: (2002)

TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727
por: Drubay, Vincent, et al.
Publicado: (2018)

TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro
por: Mao, Zhaomin, et al.
Publicado: (2017)

PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells
por: Gong, Haixia, et al.
Publicado: (2016)

Molecular characterization and expression of TGFβRI and TGFβRII and its association with litter size in Tibetan sheep
por: Zhang, Junxia, et al.
Publicado: (2023)

RIIβ‐PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning
por: Wang, Bingwei, et al.
Publicado: (2022)

Surface-bound immune complexes containing antibodies to collagen type II induce production of TNF-α, IL-1β and IL-8 from monocytes via FcγRII
por: Mullazehi, M, et al.
Publicado: (2004)

Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII
por: Pan, Ruiyan, et al.
Publicado: (2017)

Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion
por: Tang, Lipeng, et al.
Publicado: (2022)

Alternative splicing of TGF-betas and their high-affinity receptors TβRI, TβRII and TβRIII (betaglycan) reveal new variants in human prostatic cells
por: Konrad, Lutz, et al.
Publicado: (2007)

Inhibition of IκBβ/NFκB signaling prevents LPS-induced IL1β expression without increasing apoptosis in the developing mouse lung
por: McKenna, Sarah, et al.
Publicado: (2017)

Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis
por: El Kasmi, Karim C., et al.
Publicado: (2018)

β-Hydroxy-β-Methylbutyric Acid Promotes Repair of Sheep Myoblast Injury by Inhibiting IL-17/NF-κB Signaling
por: Zheng, Juan, et al.
Publicado: (2022)

TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cells
por: Baugé, Catherine, et al.
Publicado: (2015)

Crosstalk between the p38 and TGF-β signaling pathways through TβRI, TβRII and Smad3 expression in plancental choriocarcinoma JEG-3 cells
por: TAN, YUSI, et al.
Publicado: (2014)

The miR-130a-3p/TGF-βRII Axis Participates in Inhibiting the Differentiation of Fibroblasts Induced by TGF-β1
por: Liu, Yanhong, et al.
Publicado: (2021)

Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals
por: Yun, H-M, et al.
Publicado: (2013)

IKKβ/NF-κB and the miscreant macrophage
por: Timmer, Anjuli M., et al.
Publicado: (2008)

β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB
por: Liu, Shu-Guang, et al.
Publicado: (2020)

ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β
por: Robaszkiewicz, Agnieszka, et al.
Publicado: (2016)

IL1β Induces Mesenchymal Stem Cells Migration and Leucocyte Chemotaxis Through NF-κB
por: Carrero, Rubén, et al.
Publicado: (2012)

Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL‐1β/NF‐κB pathway
por: Wang, Zuqiang, et al.
Publicado: (2017)

Formononetin Attenuates IL-1β-Induced Apoptosis and NF-κB Activation in INS-1 Cells
por: Wang, Yao, et al.
Publicado: (2012)

Activation of the IL-17/TRAF6/NF-κB pathway is implicated in Aβ-induced neurotoxicity
por: Liu, Yulan, et al.
Publicado: (2023)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents
por: Linder, Thomas, et al.
Publicado: (2021)

Canonical NF-κB p65, but Not p105, Contributes to IL-1β-Induced IL-8 Expression in Cardiac Fibroblasts
por: Mizuno, Masashi, et al.
Publicado: (2022)

The NF-κB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1β
por: Kaler, Pawan, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_efinae3sb13ivil3grb66uemml