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A paradigm shift for extracellular vesicles as small RNA carriers: from cellular waste elimination to therapeutic applications

RNA interference (RNAi) is an important avenue for target-specific gene silencing that is mainly performed by either small interfering RNAs (siRNAs) or microRNAs (miRNAs). This novel method is rapidly becoming a powerful tool for gene therapy. However, the rapid degradation of siRNAs and miRNAs and...

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Detalles Bibliográficos
Autores principales: Hagiwara, Keitaro, Ochiya, Takahiro, Kosaka, Nobuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918124/
https://www.ncbi.nlm.nih.gov/pubmed/24533256
http://dx.doi.org/10.1007/s13346-013-0180-9