Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints

BACKGROUND: Adeno-associated virus (AAV) serotype 2 prevalently infects humans and is the only described eukaryotic virus that integrates site-preferentially. In a recent high throughput study, the genome wide distribution of AAV-2 integrants was determined using Integrant Capture Sequencing (IC-Seq...

Descripción completa

Detalles Bibliográficos
Autores principales: Janovitz, Tyler, Sadelain, Michel, Falck-Pedersen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918229/
https://www.ncbi.nlm.nih.gov/pubmed/24468291
http://dx.doi.org/10.1186/1743-422X-11-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918229/
https://www.ncbi.nlm.nih.gov/pubmed/24468291
http://dx.doi.org/10.1186/1743-422X-11-15

Ejemplares similares