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Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints

BACKGROUND: Adeno-associated virus (AAV) serotype 2 prevalently infects humans and is the only described eukaryotic virus that integrates site-preferentially. In a recent high throughput study, the genome wide distribution of AAV-2 integrants was determined using Integrant Capture Sequencing (IC-Seq...

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Detalles Bibliográficos
Autores principales:	Janovitz, Tyler, Sadelain, Michel, Falck-Pedersen, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918229/ https://www.ncbi.nlm.nih.gov/pubmed/24468291 http://dx.doi.org/10.1186/1743-422X-11-15

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