Cargando…

Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints

BACKGROUND: Adeno-associated virus (AAV) serotype 2 prevalently infects humans and is the only described eukaryotic virus that integrates site-preferentially. In a recent high throughput study, the genome wide distribution of AAV-2 integrants was determined using Integrant Capture Sequencing (IC-Seq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janovitz, Tyler, Sadelain, Michel, Falck-Pedersen, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918229/ https://www.ncbi.nlm.nih.gov/pubmed/24468291 http://dx.doi.org/10.1186/1743-422X-11-15

Ejemplares similares

Translocation Breakpoints Preferentially Occur in Euchromatin and Acrocentric Chromosomes
por: Lin, Cheng-Yu, et al.
Publicado: (2018)

Adeno-associated virus preferentially transduces human compared to mouse synovium
por: Jennings, K, et al.
Publicado: (2001)

Detection of recurrent rearrangement breakpoints from copy number data
por: Ritz , Anna, et al.
Publicado: (2011)

A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome
por: Lei, Mei G, et al.
Publicado: (2012)

Learning smoothing models of copy number profiles using breakpoint annotations
por: Hocking, Toby Dylan, et al.
Publicado: (2013)

An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus
por: Crowther, Andrew J., et al.
Publicado: (2018)

Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus
por: Andino, Lourdes M, et al.
Publicado: (2007)

AGE: defining breakpoints of genomic structural variants at single-nucleotide resolution, through optimal alignments with gap excision
por: Abyzov, Alexej, et al.
Publicado: (2011)

Evaluating the state of the science for adeno-associated virus integration: An integrated perspective
por: Sabatino, Denise E., et al.
Publicado: (2022)

Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo
por: Schober, Alexandra L., et al.
Publicado: (2016)

Mapping of balanced chromosome translocation breakpoints to the basepair level from microdissected chromosomes
por: Obenauf, Anna C, et al.
Publicado: (2010)

Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly
por: Le, Dinh To, et al.
Publicado: (2019)

Adeno-associated virus receptor complexes and implications for adeno-associated virus immune neutralization
por: Large, Edward E., et al.
Publicado: (2023)

Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty
por: Longo, Mark S, et al.
Publicado: (2009)

Targeted Next-Generation Sequencing at Copy-Number Breakpoints for Personalized Analysis of Rearranged Ends in Solid Tumors
por: Kim, Hyun-Kyoung, et al.
Publicado: (2014)

GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes
por: van den Broek, Evert, et al.
Publicado: (2017)

Antimicrobial resistance to benzylpenicillin in invasive pneumococcal disease in Belgium, 2003–2010: the effect of altering clinical breakpoints
por: GOOSSENS, M. C., et al.
Publicado: (2013)

My Pathway to Adeno-Associated Virus and Adeno-Associated Virus Gene Therapy: A Personal Perspective
por: Carter, Barrie J.
Publicado: (2020)

LongAGE: defining breakpoints of genomic structural variants through optimal and memory efficient alignments of long reads
por: Tran, Quang, et al.
Publicado: (2020)

Cassis: detection of genomic rearrangement breakpoints
por: Baudet, Christian, et al.
Publicado: (2010)

MATCHCLIP: locate precise breakpoints for copy number variation using CIGAR string by matching soft clipped reads
por: Wu, Yinghua, et al.
Publicado: (2013)

The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
por: Carvalho, Diana, et al.
Publicado: (2014)

A palindromic RNA sequence as a common breakpoint contributor to copy-choice recombination in SARS-COV-2
por: Gallaher, William R.
Publicado: (2020)

Case Report: Neuroblastoma Breakpoint Family Genes Associate With 1q21 Copy Number Variation Disorders
por: Zhu, Lijuan, et al.
Publicado: (2021)

IN VITRO TRANSFORMATION BY THE ADENOVIRUS-SV40 HYBRID VIRUSES : II. CHARACTERISTICS OF THE TRANSFORMATION OF HAMSTER CELLS BY THE ADENO 2-, ADENO 3-, AND ADENO 12-SV40 VIRUSES
por: Black, Paul H., et al.
Publicado: (1967)

Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans
por: Silva-García, Carlos G., et al.
Publicado: (2019)

1600. Closing the gap on moxifloxacin breakpoints for Stenotrophomonas maltophilia
por: Stone, Tyler J, et al.
Publicado: (2020)

Augmentation of Transgene-Encoded Protein After Neonatal Injection of Adeno-Associated Virus Improves Hepatic Copy Number Without Immune Responses
por: Tai, Denise S., et al.
Publicado: (2015)

A retrograde adeno-associated virus for collecting ribosome-bound mRNA from anatomically defined projection neurons
por: Cook-Snyder, Denise R., et al.
Publicado: (2015)

No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients
por: Nissen, Kari K, et al.
Publicado: (2012)

Effects of Cellular Methylation on Transgene Expression and Site-Specific Integration of Adeno-Associated Virus
por: Chanda, Diptiman, et al.
Publicado: (2017)

Prevalent and Disseminated Recombinant and Wild-Type Adeno-Associated Virus Integration in Macaques and Humans
por: Martins, Kelly M., et al.
Publicado: (2023)

Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5
por: Schuster, Daniel J., et al.
Publicado: (2014)

Characterization of Chromosomal Breakpoints in 12 Cases with 8p Rearrangements Defines a Continuum of Fragility of the Region
por: Redaelli, Serena, et al.
Publicado: (2022)

Pharmacology of Recombinant Adeno-associated Virus Production
por: Penaud-Budloo, Magalie, et al.
Publicado: (2018)

An essential receptor for adeno-associated virus infection
por: Pillay, S., et al.
Publicado: (2016)

Cryo-electron Microscopy of Adeno-associated Virus
por: Stagg, Scott M., et al.
Publicado: (2022)

Fluorescence Microscopy in Adeno-Associated Virus Research
por: Golm, Susanne K., et al.
Publicado: (2023)

Nuclear Import of Adeno-Associated Viruses Imaged by High-Speed Single-Molecule Microscopy
por: Junod, Samuel L., et al.
Publicado: (2021)

Integrative Analysis of the AMPK subunits in Colorectal Adeno Carcinoma
por: T B, Beena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qrqk45sgml18kng373q1o6rimb