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Multicomponent synthesis and anticonvulsant activity of monocyclic 2,6-diketopiperazine derivatives

In this study, a series of diastereomerically pure monocyclic 2,6-diketopiperazine (2,6-DKP) derivatives were synthesized. The key synthetic step involved a multicomponent Ugi five-center, four-component reaction which was used to generate the convertible tert-butylamidoesters with both good yields...

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Detalles Bibliográficos
Autores principales: Dawidowski, Maciej, Turło, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918383/
https://www.ncbi.nlm.nih.gov/pubmed/24587688
http://dx.doi.org/10.1007/s00044-013-0800-4