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Multicomponent synthesis and anticonvulsant activity of monocyclic 2,6-diketopiperazine derivatives
In this study, a series of diastereomerically pure monocyclic 2,6-diketopiperazine (2,6-DKP) derivatives were synthesized. The key synthetic step involved a multicomponent Ugi five-center, four-component reaction which was used to generate the convertible tert-butylamidoesters with both good yields...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918383/ https://www.ncbi.nlm.nih.gov/pubmed/24587688 http://dx.doi.org/10.1007/s00044-013-0800-4 |