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IVIVC from Long Acting Olanzapine Microspheres

In this study, four PLGA microsphere formulations of Olanzapine were characterized on the basis of their in vitro behavior at 37°C, using a dialysis based method, with the goal of obtaining an IVIVC. In vivo profiles were determined by deconvolution (Nelson-Wagner method) and using fractional AUC. T...

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Detalles Bibliográficos
Autores principales: D'Souza, Susan, Faraj, Jabar A., Giovagnoli, Stefano, DeLuca, Patrick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918854/
https://www.ncbi.nlm.nih.gov/pubmed/24578707
http://dx.doi.org/10.1155/2014/407065