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Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1
Replication of HIV-1 and other retroviruses is dependent on numerous host proteins in the cells. Some of the host proteins, however, function as restriction factors to block retroviral infection of target cells. The host protein SAMHD1 has been identified as the first mammalian deoxynucleoside triph...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918895/ https://www.ncbi.nlm.nih.gov/pubmed/24523981 http://dx.doi.org/10.1155/2013/728392 |