Broad Antigenic Coverage Induced by Viral cDNA Library-based Vaccination Cures Established Tumors

We show here that a cDNA library of normal tissue, expressed from a highly immunogenic viral platform, cures established tumors of the same histological type from which the cDNA library was derived. With suboptimal vaccination, immune escape was possible, but only when tumor cells were forced to acq...

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Detalles Bibliográficos
Autores principales: Kottke, Timothy, Errington, Fiona, Pulido, Jose, Galivo, Feorillo, Thompson, Jill, Wongthida, Phonphimon, Diaz, Rosa Maria, Chong, Heung, ILett, Elizabeth, Chester, John, Pandha, Hardev, Harrington, Kevin, Selby, Peter, Melcher, Alan, Vile, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918897/
https://www.ncbi.nlm.nih.gov/pubmed/21685898
http://dx.doi.org/10.1038/nm.2390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918897/
https://www.ncbi.nlm.nih.gov/pubmed/21685898
http://dx.doi.org/10.1038/nm.2390

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