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Immunomodulation in Human Dendritic Cells Leads to Induction of Interferon-Gamma Production by Leishmania donovani Derived KMP-11 Antigen via Activation of NF-κB in Indian Kala-Azar Patients

Dendritic cells (DCs) and macrophages (MΦs) are well-known antigen presenting cells with an ability to produce IL-12 which indicates that they have potential of directing acquired immunity toward a Th1-biased response. The aim of this study was to examine the effect of Leishmania specific KMP-11 ant...

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Detalles Bibliográficos
Autores principales: Chaudhary, Rajesh, Amit, Ajay, Yadav, Anupam, Singh, Anurag, Kumar, Vikash, Singh, S. K., Narayan, Shyam, Rabidas, Vidyanand, Pandey, K., Kumar, Anil, Das, Pradeep, Bimal, Sanjiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919100/
https://www.ncbi.nlm.nih.gov/pubmed/24587999
http://dx.doi.org/10.1155/2014/947606