GpIbα Interacts Exclusively with Exosite II of Thrombin()

Activation of platelets by the serine protease thrombin is a critical event in haemostasis. This process involves the binding of thrombin to glycoprotein Ibα (GpIbα) and cleavage of protease-activated receptors (PARs). The N-terminal extracellular domain of GpIbα contains an acidic peptide stretch t...

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Detalles Bibliográficos
Autores principales: Lechtenberg, Bernhard C., Freund, Stefan M.V., Huntington, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919161/
https://www.ncbi.nlm.nih.gov/pubmed/24316004
http://dx.doi.org/10.1016/j.jmb.2013.11.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919161/
https://www.ncbi.nlm.nih.gov/pubmed/24316004
http://dx.doi.org/10.1016/j.jmb.2013.11.027

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