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A Structure of a Collagen VI VWA Domain Displays N and C Termini at Opposite Sides of the Protein

Von Willebrand factor A (VWA) domains are versatile protein interaction domains with N and C termini in close proximity placing spatial constraints on overall protein structure. The 1.2 Å crystal structures of a collagen VI VWA domain and a disease-causing point mutant show C-terminal extensions tha...

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Detalles Bibliográficos
Autores principales: Becker, Ann-Kathrin A., Mikolajek, Halina, Paulsson, Mats, Wagener, Raimund, Werner, Jörn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919171/
https://www.ncbi.nlm.nih.gov/pubmed/24332716
http://dx.doi.org/10.1016/j.str.2013.06.028