Cargando…

Three-dimensional structure of a Streptomyces sviceus GNAT acetyltransferase with similarity to the C-terminal domain of the human GH84 O-GlcNAcase

The mammalian O-GlcNAc hydrolysing enzyme O-GlcNAcase (OGA) is a multi-domain protein with glycoside hydrolase activity in the N-terminus and with a C-terminal domain that has low sequence similarity to known acetyltransferases, prompting speculation, albeit controversial, that the C-terminal domain...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yuan, Roth, Christian, Turkenburg, Johan P., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919268/
https://www.ncbi.nlm.nih.gov/pubmed/24419391
http://dx.doi.org/10.1107/S1399004713029155