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PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution
Correctly estimating isoform-specific gene expression is important for understanding complicated biological mechanisms and for mapping disease susceptibility genes. However, estimating isoform-specific gene expression is challenging because various biases present in RNA-Seq (RNA sequencing) data com...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919567/ https://www.ncbi.nlm.nih.gov/pubmed/24362841 http://dx.doi.org/10.1093/nar/gkt1304 |