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Interaction-based discovery of functionally important genes in cancers

A major challenge in cancer genomics is uncovering genes with an active role in tumorigenesis from a potentially large pool of mutated genes across patient samples. Here we focus on the interactions that proteins make with nucleic acids, small molecules, ions and peptides, and show that residues wit...

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Detalles Bibliográficos
Autores principales: Ghersi, Dario, Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919581/
https://www.ncbi.nlm.nih.gov/pubmed/24362839
http://dx.doi.org/10.1093/nar/gkt1305