SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor

In addition to the glucocorticoids, the glucocorticoid receptor (GR) is regulated by post-translational modifications, including SUMOylation. We have analyzed how SUMOylation influences the activity of endogenous GR target genes and the receptor chromatin binding by using isogenic HEK293 cells expre...

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Detalles Bibliográficos
Autores principales: Paakinaho, Ville, Kaikkonen, Sanna, Makkonen, Harri, Benes, Vladimir, Palvimo, Jorma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919585/
https://www.ncbi.nlm.nih.gov/pubmed/24194604
http://dx.doi.org/10.1093/nar/gkt1033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919585/
https://www.ncbi.nlm.nih.gov/pubmed/24194604
http://dx.doi.org/10.1093/nar/gkt1033

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