Cargando…

SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor

In addition to the glucocorticoids, the glucocorticoid receptor (GR) is regulated by post-translational modifications, including SUMOylation. We have analyzed how SUMOylation influences the activity of endogenous GR target genes and the receptor chromatin binding by using isogenic HEK293 cells expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Paakinaho, Ville, Kaikkonen, Sanna, Makkonen, Harri, Benes, Vladimir, Palvimo, Jorma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919585/
https://www.ncbi.nlm.nih.gov/pubmed/24194604
http://dx.doi.org/10.1093/nar/gkt1033

Ejemplares similares