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Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in Arabidopsis

RecQ helicases are critical for the maintenance of genomic stability. The Arabidopsis RecQ helicase RECQ4A is the functional counterpart of human BLM, which is mutated in the genetic disorder Bloom’s syndrome. RECQ4A performs critical roles in regulation of homologous recombination (HR) and DNA repa...

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Detalles Bibliográficos
Autores principales: Schröpfer, Susan, Kobbe, Daniela, Hartung, Frank, Knoll, Alexander, Puchta, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919593/
https://www.ncbi.nlm.nih.gov/pubmed/24174542
http://dx.doi.org/10.1093/nar/gkt1004