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Eukaryotic rpL10 drives ribosomal rotation

Ribosomes transit between two conformational states, non-rotated and rotated, through the elongation cycle. Here, we present evidence that an internal loop in the essential yeast ribosomal protein rpL10 is a central controller of this process. Mutations in this loop promote opposing effects on the n...

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Detalles Bibliográficos
Autores principales: Sulima, Sergey O., Gülay, Suna P., Anjos, Margarida, Patchett, Stephanie, Meskauskas, Arturas, Johnson, Arlen W., Dinman, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919601/
https://www.ncbi.nlm.nih.gov/pubmed/24214990
http://dx.doi.org/10.1093/nar/gkt1107