Cargando…

Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork

Two models have been proposed for triggering release of the lagging strand polymerase at the replication fork, enabling cycling to the primer for the next Okazaki fragment—either collision with the 5′-end of the preceding fragment (collision model) or synthesis of a new primer by primase (signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Quan, McHenry, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919610/
https://www.ncbi.nlm.nih.gov/pubmed/24234450
http://dx.doi.org/10.1093/nar/gkt1098